Introduction: Isocyanate Compounds NCO groups react easy with biological molecules & considered to be a powerful respiratory irritant and major cause of asthma, bronchitis chemical. Studies /investigations have shown that the risk of death from lung cancer is spreading among car painters. This study aimed to identify amount of worker with Physical contact on reduction of this contaminant in the work places produces isocyanates are about 3 million tons annually and 280000 workers are in contact with it in America. Extensive researches on the 57000 of Painter are shown that the risk of death from lung cancer is very high among workers of painter. Toluene diisocyanate (TDI) have used as the most important industrial intermediates in industry. The purpose of epidemiological studies of isocyanate compounds is appointment occupational exposure of workers. In order to reduce these pollutants in the workplace, the employers must know the safety rules and use effectively controls. The purpose of performance of this project is survey impact of control on reducing the amount of isocyanate in air of workplace.
Method: 10%of car painters were selected in Karaj city, and then 58 air samples were collected by using standard methods. Analysis of samples was performed by HPLC with niosh 5522 method. Statistical analysis was analysis by SPSS software.
Result: Average of age, work history and work history with pain, in a sequence were 36.8, 18.25, 16.65.35.5% was smokers.63.8% of workshop had industrial ventilation. The Pollutant concentration average MDI, TDI was 7.9 mg/m3 and 1.05 that the highest concentration was related to No 9. Between smoking and respiratory problem among workers significant relations were found (p<0.002). In statistical analysis correlation coefficient (0.5) was observed between the temperature factor and increase HDI concentration pollutant concentration is significant between groups, where as it is not the same inside groups.
Conclusion: This is correlation between workshop temperature & amount of pollutants and it increase at the end of the shift. Most of the samples had more concentration then standard. High concentration of pollutants, lack of ventilation system in 36% of the workshops & and smoking in the 35.5% of workers could increase diseases related to compounds isocyanate in future.